Squalane
Evidence types available
A hydrogenated and stabilised form of squalene — a lipid naturally produced by human sebaceous glands that declines measurably with age. Squalane (not squalene) is stable for use in cosmetics and functions as a lightweight, non-greasy emollient that replenishes skin lipids and reduces transepidermal water loss without occluding pores. Human skin recognises it as a native lipid, making it exceptionally well-tolerated and non-comedogenic across most skin types. Sourced from olives, sugarcane, or sharks (the latter now largely discontinued). Human clinical evidence for barrier repair and skin softening is solid; typically used at 1–100% depending on the formulation. One of the most broadly compatible oils in skincare.
How squalane works in skin
Mimics skin's own sebum
Identical structure to natural squalene
Occlusive barrier seal
Prevents moisture escaping the surface
Full cited breakdown coming soon. In the meantime the summary above reflects the current research.