Centella Asiatica
Evidence types available
An herbaceous plant used in traditional Ayurvedic and TCM medicine that has accumulated a meaningful modern evidence base. Active compounds — asiaticoside, asiatic acid, madecassic acid, and madecassoside — stimulate fibroblast proliferation and collagen synthesis, and accelerate wound healing. Human RCT evidence for hypertrophic scar treatment and skin repair is solid. Anti-inflammatory effects are also documented in human studies. One of the few traditional botanical ingredients in skincare where the mechanism is understood at a cellular level and where RCT data at clinically relevant concentrations exists.
How centella asiatica works in skin
Madecassoside calms inflammation
Reduces redness and sensitisation
↑ Collagen via TGF-β pathway
Asiaticoside stimulates wound repair
Full cited breakdown coming soon. In the meantime the summary above reflects the current research.